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Specifications subject to change without notice.In vitro scratch wound healing assay, a simple and low-cost technique that works along with other image analysis tools, is one of the most widely used 2D methods to determine the cellular migration and proliferation in processes such as regeneration and disease. The trademarks used herein are the property of Molecular Devices, LLC or their respective owners. Ordering informationĪngiogenesis Application Module for MetaXpress SoftwareĬheck our web site for a current listing of worldwide distributors.įOR RESEARCH USE ONLY.
#Angiogenesis analyze for imagej software software
High-end hit selection and quality control is available through AcuityXpress™ Software, the data analysis software integrated to the Complete Imaging Solution from Molecular Devices.ĪcuityXpress Software features Interactive Image Zoom drill down for bidirectional interaction between images and numerical data. Image analysis can be distributed to the MetaXpress ® PowerCore™ high-throughput image analysis platform, providing unparalleled performance in the race to identify “hits.” Increasing image analysis speed by 10-to 30-fold virtually eliminates image analysis bottlenecks and enables multiple ImageXpress systems to run in parallel. Image acquisition with ImageXpress ® Instrumentation provides the fastest reading times for large libraries and a great flexibility in acquisition set-up for research through screening. The fastest workflow from acquisition to hit selection
#Angiogenesis analyze for imagej software series
These powerful macros record and perform a series of tasks without the user having to know a programming language. MetaXpress Software and the Angiogenesis Application Module are seamlessly integrated with the flexibility of MetaMorph ® Software and its advanced automation macros.
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Mean node area Further customization through macros The module generates 14 parameters for each image, including: Optionally specify the reporting parameters.Set the intensity above local background.Specify the minimum and maximum tube widths.ABC enables vessel detection even with highly variable background fluorescence within a single image.Įasy configuration and multiparametric analysisĪ simple interface minimizes setup efforts and analysis settings can be configured once and saved for future use or customized to fit a specific experiment The module utilizes Adaptive Background Correction (ABC) which adapts the vessel detection algorithm to the local intensity ranges outside the vessels to provide the most robust segmentation available in an image-based screening system. To capture the three-dimensional behavior of cells, MetaXpress Software allows for a unique z-series acquisition and the collapse of all the z-series in a single “best focus” image. The module also provides the fastest image acquisition and analysis through integration with Molecular Devices’ complete solution for cellular imaging.
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The Angiogenesis Application Module for MetaXpress ® Software from Molecular Devices is designed to tackle the challenges of the analysis of tube formation assays with a unique image processing approach and a simple set-up. Indeed, while some tubes develop parallel to the surface, uneven surfaces drive some tubes to grow perpendicular to it instead. Tube formation in three dimensions poses significant image analysis challenges. To mimic natural tube formation in vitro, cells are grown in a three-dimensional matrix and tubes, reminiscent of the in vivo behavior develop. One of the morphological changes that can be observed in angiogenesis is tube formation. Angiogenesis-dependent diseases-such as cancer, diabetic retinopathy, psoriasis, coronary artery disease, stroke and rheumatoid arthritis- result when new blood vessels either grow excessively or insufficiently. In many serious diseases, the body loses control over angiogenesis. Angiogenesis occurs in the healthy body for healing wounds and restoring blood flow to tissues after injury or insult. High-Content Screening with AgileOptix TechnologyĪngiogenesis is the growth of new blood vessels and is an important natural process occurring in the body, both in health and disease.PROTEIN DETECTION, QUANTITATION, ANALYSIS.NUCLEIC ACID (DNA/RNA) DETECTION & ANALYSIS.SpectraTest Validation Plates and Recertification.GXP SOFTWARE INSTALLATION AND VALIDATION.COVID-19 RESPONSE - We are committed to supporting our scientific community during this pandemic.